Summary: This review presents a thorough investigation of the role of CD47 in gastrointestinal cancers.We performed a comprehensive, in-depth review of over 100 preclinical and clinical studies focused on inhibiting CD47.The research highlights the potential of targeted CD47 to enhance existing treatments by boosting the immune response to cancer c
The use of Outdoor Rocking Chair transcranial electrical stimulation (TES) as a method to augment neural activity has increased in popularity in the last decade and a half.The specific application of TES to the left prefrontal cortex has been shown to produce broad cognitive effects; however, the neural mechanisms underlying these effects remain un
The study examines the mechanisms of censorship restrictions on Russian periodical press that had become widespread by the beginning of the 20th century.It explores the history of the development of censorship during the post-reform era and the stages of reorganization of the censorship apparatus in the context of changing Russian realities in the
Given the problem of three-sources uncertainty in aero engine degradation process and the assumption of normal distribution of measurement error in existing research, a Wiener process aero engine residual useful life time(RUL) prediction method with logistic distribution of measurement error was proposed.Firstly, the performance degradation model w
Hypoxia is a typical characteristic of most solid malignancies, which has multiple effects on malignant phenotypes and biological behaviors of tumors including epithelial-mesenchymal-transition (EMT), invasion, migration, metastasis, autophagy, stem cell maintenance, pathological angiogenesis, drug resistance, and immunosuppression.Rcentlyumoand re